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From baseline to the study end, semaglutide increased subjects estimated retention of gastric contents after eating radioactively labelled solid meals as follows: 1 hour by 3.5% 2 hours by 25.5% 3 hours by 28.0% 4 hours by 30.0% The time it took for half the radiolabeled meal to empty from the stomach was significantly longer in the semaglutide group than the placebo group (171 vs

10.1242/jcs.02932 90 MillsS

Each vial is independently verified to 99% HPLC purity with a Certificate of Analysis available on request

The estimated treatment difference for tirzepatide versus insulin degludec ranged from -0.59% to -1.04%, with all tirzepatide doses demonstrating statistical significance