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DA5-CH and semaglutide protect against neurodegeneration and reduce -Synuclein levels in the 6-OHDA Parkinsons disease rat model

Of note, the presentation at the NPWH annual conference in Savannah, Georgia, in October 2019, on which this article is based, focused primarily on the treatment of HSDD in premenopausal women

Observed mechanisms include direct neuronal damage, disruption of key neurotransmitter pathways such as AChE activity, induction of cellular stress responses, and alterations in both locomotor and spontaneous activity patterns, particularly in Drosophila

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