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However, molecular signaling of BSO-induced apoptosis is poorly understood, and, recently, it has been demonstrated that in different leukaemia and lymphoma cells, the death receptor-mediated apoptotic pathway, induced by arsenic trioxide plus BSO, is triggered via JNK activation [58]

Important areas of further study include continued elucidation of immunopathogenesis and genetic associations, investigation into potential biomarkers to aid in diagnosis and prognostication, and standardization of optimal treatment

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Dosage accuracy Mowrer suggests that compounded medications might present a risk of inconsistent or inaccurate dosing