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10.1371/journal.pone.0196405 74

Selenium in pregnancy: is selenium an active defective ion against environmental chemical stress

Conclusions Our data implicate that exogenous antioxidants NAC and GSH, by reducing the intracellular ROS levels and inducing TMBIM expression, promoted HCC formation and tumor growth, and counteracted the therapeutic effect of Sorafenib

It is considered to be consisted of central, peripheral or transitional zone and composed of three different types of cells: glandular epithelial cells, smooth muscle cells and stromal cells (Figure 1)