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Antidepressants Antidepressants have an effect on some of the neurotransmitters, like norepinephrine and serotonin, which can have an effect on pain, explains Williams

Higher doses of Tirzepatide led to greater weight loss over time, with the most effective doses being 10-15 mg

This includes alterations in intestinal flora composition, regulation of genes associated with bile acid synthesis and transport, and modulation of intestinal endocrine hormone secretion