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We utilised quantile g-computation that can estimate the combined effect of a mixture of health-promoting and health-constraining exposures, unlike inferential approaches that examine the effects of individual exposures while holding other exposures constant [41]

You cannot design a system where opioids are easy and PT is hard, and then be surprised when people choose opioids

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People who never used e-cigarettes were 1.5 times more likely to begin using after receiving coupons, those who formerly used e-cigarettes were 1.4 times more likely to relapse, and current users were nearly 1.3 times more likely to continue using than people who did not receive coupons