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I was especially struck by the contrast between Mukherjees willingness to, if not forgive, at least understand the horrible mistakes that were made in early cancer treatment (e.g., radical mastectomies for everyone!) and his barely suppressed rage at the range and depth of devastation caused by cigarette smoking: It remains an astonishing, disturbing fact that in Americaa nation where nearly every new drug is subjected to rigorous scrutiny as a potential carcinogen, and even the bare hint of a substances link to cancer ignites a firestorm of public hysteria and media anxiety-one of the most potent and common carcinogens known to humans can be freely bought and sold at every corner store for a few dollars.

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So if the p53 gene now has a mutation, the p53 protein cant do its job to get rid of cells with mutations

Studies on Ottoman Society and Culture: 16th18th Centuries