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Greater trochanteric pain syndrome is relatively common in both physically active and sedentary patients affecting 15.0% in women and 8.5% in men (Segal et all, 2007)

Its inclusion in the Category 2 restricted list has drawn criticism from clinicians who point to its legitimate international approval record as evidence that the safety concerns cited by the FDA are inconsistent with the global clinical literature

Overall, BPC-157 is thought to act through a coordinated network of biological pathways rather than a single receptor-mediated mechanism