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The codes are used everywhere from insurance companies to hospitals to nursing homes, so everyone has to make the transition simultaneously at a time when dealing with big changes such as electronic records requirements and the Affordable Care Act have already stretched them thin

Thus, lower dopamine levels may activate high affinity receptors (D3, D4, and D5) to drive one function, while high dopamine levels could activate both the low- (D1 and D2) and high-affinity dopamine receptors, potentially activating other distinct functions through multiple receptors

But scientists quickly realized its effects were far from localized