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IN OUR INSTITUTION, we have had recent requests for information on manipulation of glutathione (GSH) concen-trations in patients, and have observed the recent and growing body of literature on this topic

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This is not surprising, considering that tirzepatide and semaglutide evoked more pronounced TBWL and also have glucose-lowering effects by slowing gastric emptying, stimulating insulin secretion and inhibiting glucagon secretion in a glucose-dependent manner, independent of their effects on body weight 50,51

Finally, current challenges and future prospects for advanced applications of MOFs-based biosensors are highlighted