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[3] However, unlike pralmorelin (GHRP-2) and GHRP-6, but similarly to growth hormone-releasing hormone (GHRH), ipamorelin does not stimulate the secretion of adrenocorticotropic hormone (ACTH), or cortisol, and is highly selective for inducing the secretion only of GH

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Insulin resistance contributes to the downregulation of muscle contractile protein synthesis by inhibiting insulins anabolic signaling pathway and simultaneously upregulating protein degradation via the ubiquitinproteosome pathway [30]