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Studies focus on its ability to inhibit matrix metalloproteinases (MMPs), affect immune cell activity, and improve chemotherapy outcomes
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A hallmark of the stress is now known to include a response at the protein level, which occurs much more rapidly than the transcriptional response and can include posttranscriptional events that provide just in time production of genes such as rapid reprogramming of translation through a variety of mechanismsuORFs [40], stress granules [41], and active blocking of the exit of ribosomal subunits through the nuclear pore [42] to name a few
Anti-xCT immunization may be utilized as an adjuvant therapy in patients with breast cancer who are resistant to conventional therapies
