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The oxidative stress markers CMC (edf = 4.580, p-value = 0.002) and CML (edf = 4.456, p-value = 0.007) displayed nonlinear relationships with mental health scores, with cognitive impairments being particularly pronounced in patients with intermediate levels of these markers (Fig.s 3B &C)

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With severe Cu deficiency, the number and ability of neutrophils to generate O 2 and kill absorbed microorganisms, T-cell proliferation and IL-2 production decrease (96)

Pediatr Nephrol 11:280284 Tnshoff B, Heinrich U, Mehls O (1991) How safe is the treatment of uraemic children with recombinant human growth hormone