Additional file 2: Figure S2 (download TIFF Phylogenetic tree based on 16S rRNA gene sequence of the isolate MBM and other related species from the NCBI database
(Guo et al., 2021)., CY treatment for 2 weeks in an MCAO rat model improved neurological function, reduced brain water content, and diminished infarct size by inhibiting the accumulation of ferrous ions and ROS, and reversing the expression levels of ACSL4, TfR1, GPX4, and FTH1 in CIRI (Table 4)
So there is a possibility the favourable findings for this group of drugs may relate to the people who take them having some additional socioeconomic advantages, including diet, greater or more frequent access to exercise, and maybe higher or longer levels of education, that have also offered some other forms of protection. Martin Whyte, an associate professor at the University of Surrey also added, Notably, the authors did not provide detailed information about the characteristics of patients in each group, either before or after statistical matching, and treatment duration for either GLP-1 drugs or metformin was not reported
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