Unlike oral supplements, which face the gauntlet of our digestive system (and often get broken down, resulting in as little as 20-50% absorption), intravenous delivery bypasses the gut entirely
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In preclinical heart failure models, NNMT enzyme inhibition markedly reduced cardiac 1-MNA (by 77.1%), improved cardiac function, reduced left ventricular hypertrophy and fibrosis, and decreased pro-inflammatory gene expression