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The 2012 fungal meningitis outbreak caused by contaminated compounded medications from a Massachusetts pharmacy remains a landmark case showing catastrophic consequences of poor sterile compounding practices
Clinical trials demonstrate up to 26.1% fat mass reduction at the 8mg dose while maintaining favorable lean mass preservation comparable to other obesity treatments
Drucker and Asa, 1988
One meta-analysis compared the highest dose of tirzepatide (15 mg) to the highest dose of semaglutide (2 mg) and found that tirzepatide resulted in a greater weight loss at a 17.8% reduction in body weight versus 12.4% for semaglutide
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