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Taken together, these innovative delivery platforms have been shown to enhance the transdermal bioavailability of flavonoids and improve their pharmacological effects and biocompatibility

Berberine regulates the mRNA levels of glucose-regulated protein 78 (GRP78), CCAAT/enhancer binding protein (C/EBP) -homologous protein (CHOP), procaspase-3/9/12 in Alzheimers disease rats hippocampus, which involve in the endoplasmic reticulum stress pathway (Xuan et al., 2020)

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