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The primary endpoint was percent change in body weight from baseline to week 48

While much of the research remains preliminary, MT-1 continues to be a central compound of interest in studies of melanocortin receptor signaling and its broader implications in experimental biology

Despite a significant improvement in the treatment of T2D and CVD over the past few decades, reducing CVD in patients with T2D solely with an optimal glycemic control has been challenging [2]

Furthermore, the percentage of bihormonal insulin + glucagon + cells was higher in liraglutide-treated WT mice compared with that in KO mice (Figure 6, A and B