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OptumRx, 2026 formulary update and prior authorization criteria In February 2026, OptumRx removed the BMI requirement from its cardiovascular reauthorization criteria for Wegovy, simplifying continued authorization for UHC members using the CV indication

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This creates elevated catecholamines (anxiety, insomnia, racing heart), elevated histamine (flushing, hives, food reactions), impaired thiopurine drug metabolism, and impaired arsenic detoxification

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