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Consistent with what was observed with trichloroethylene, the GSH- S -conjugate of 4-hydroxynonenal (HNE) causes a loss in cell viability in GT-expressing cells (Enoiu et al., 2002)

The fast reactivity of PAT was confirmed in vivo and in vitro where no PAT could be detected in human serum after ingestion of PAT containing apple juice and a reduction of PAT levels by 94% within two minutes of incubation of PAT in a human blood sample (Rychlik 2003)

~3.33mg/mL BPC-157