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Your healthcare provider may recommend diagnostic evaluation, including upper endoscopy (esophagogastroduodenoscopy) if you have alarm symptoms, refractory GERD despite optimized therapy, or risk factors for Barrett's esophagus (such as chronic GERD plus male sex, age over 50, White race, central obesity, tobacco history, or family history)

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Commonly used human hepatocyte cell lines include hepatocellular carcinoma cell lines such as HepG2, human hepatoma cells and protein phospholipase C, which are taken from human liver cancer tissues and normal hepatocyte cell lines such as LO2

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