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FIGURE 5 Age- and sex-dependent effects of pomegranate extract on TMAO response Although the overall effect of the pomegranate extract on plasma TMAO AUC was null ( P = 0.945), we observed that the participants with increasing TMAO were older (Figure 6A), and in particular the three oldest women ( n = 3

The clinical approach remains sound regardless of whether the specific mechanism is correct

Nausea and vomiting, which are common side effects particularly early in semaglutide treatment, can cause mild dehydration