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The following represents a theoretical ultra-conservative approach based on monotherapy principles: Hypothetical Ultra-Conservative Schedule: This extended 24-week titration period doubles the typical monotherapy escalation timeline , reflecting the complete absence of interaction data and the overlapping side effect profiles

HPLC may provide peptide-purity information, while the arginine-associated component may require separate analysis

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[VERIFY: confirm typical timeline observations with clinical team] SS-31 has been studied in multiple clinical trials, including the Phase 3 TAZPOWER trial and earlier Phase 2 studies in heart failure, with a consistent safety profile