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2 for the pathways metabolic affected by UGT)

Reduction in both glutamate and glycine levels may also conspire to hinder antioxidant defense, since these amino acids are principal components of the reducing agent, glutathione (Extended Data Fig

This study is to explore a GSH-responsive AP probe-net, which can be activated by the abundant GSH in ATC cells to generate reactive alkoxyamine, and the formed alkoxyamine can trap AP sites and block the APE1 activity, leading to ATC cell death but less adverse effects towards normal cells

The key is finding a timing schedule that promotes consistent adherence while optimizing absorption and minimizing any potential side effects