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Study Selection The criteria for inclusion were as follows: 1) phase 3 RCTs that enrolled patients (18 years of age or older) with T2D and compared subcutaneous or oral semaglutide administration with placebo or other anti-diabetic drugs

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The hormones produced and secreted via various glands situated throughout the body are part of the endocrine system

Validation of the RNA seq data by evaluation of a few genes by q-RT-PCR To validate the accuracy of our RNA-Seq data, we selected representative genes from different pathways for further analysis