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When these organs are functioning at a reduced capacity, the drug can remain active longer

The LS mean differences across interactions provided further information about the reaction to challenge material within and between severity categories

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Antman E, Hand M, Armstrong P, Bates E, Green L, Halasyamani L, Hochman J, Krumholz H , Lamas G, Mullany C, Pearle D, Sloan M, Smith S, Anbe D, Kushner F, Ornato J, Pearle D, Sloan M, Jacobs A, Adams C, Anderson J, Buller C, Creager M, Ettinger S, Halperin J, Hunt S, Lytle B, Nishimura R, Page R, Riegel B, Tarkington L, Yancy C