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Among the eight tested compounds, DJX-A-KA and DJX-A-KG which incorporate the previously reported 2 H -azirine warhead known to recruit NEDD4 exhibited significant KRAS G12C degradation

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Q: Can this medium-depth peel be safely administered to darker skin profiles (Fitzpatrick scales IV-VI)

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The clinical version is narrower, better defined, and more reliably delivered