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In myeloid cell lines there was a more differential effect: when quercetin and apigenin were used in combination with each topoisomerase II inhibitor, there was a synergistic/additive decrease in cell proliferation, cell accumulation in G 2 M and S phase of the cell cycle and an increase in apoptosis

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Quantitative histological analyses have demonstrated increased collagen and reticulin synthesis, enhanced neovascularization, and improved wound tensile strength in rodent models following BPC 157 administration (Seiwerth et al