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This method was designed to minimize the use of organic solvents, resulting in a more sensitive and cost-effective approach

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The tested animals that were listed in the patent include rats, mice, rabbits, guinea pigs and pigs, as well as a single study in humans

Numerous retrospective studies and meta-analyses have confirmed that a low preoperative PNI is an independent risk factor for overall complications, severe complications, pulmonary infections, and anastomotic leakage after esophagectomy (96, 97)