Negative evidence: A study in Indonesian individuals showed that supplementation with glutathione combined with vitamin C, alpha-lipoic acid, and zinc did not significantly lighten skin compared to placebo (Sitohang et al., J Clin Aesthet Dermatol, 2021) [63]
However, an RCT on 35 patients with migraine, showed that supplementation with N-acetylcysteine (1,200 mg), vitamin E (500 IU), and vitamin C (1,000 mg) daily for 3 months resulted in lower frequency, severity, and duration of headaches and lower acute medication use (90)
Cochrane Datatabase Syst Rev 8:008502 Nimmerrichter AA, Walter H, Gutierrez-Lobos KE, Lesch OM (2002) Double blind controlled trial of gamma-hydroxybutyrate and clomethiazole in the treatment of alcohol withdrawal
The companys proposition is bold: delay the grey. Why put up with grey hair when we could pop a new pill to replenish [our] body with the vitamins, minerals and anti-oxidants it needs to hold onto our natural hair colour
