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For instance, it is reasonable to say a patient who is only able to tolerate a maintenance dose of 0.5mg may experience overdose severity symptoms if they were to take 3 to 4 weeks worth of doses (approximately 1.5mg to 2 mg) all at once, while other patients may not experience severe symptoms unless significantly higher amounts were administered

The cleared lysate was purified on an immobilized subtilisin column (Potomac Affinity Proteins, USA), using a method similar to that described previously 82

Cest notamment le cas du foie, considr comme lun des principaux rservoirs, mais aussi des reins, des poumons, du pancras et des globules rouges