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Their complementary mechanisms one acting primarily through growth factor upregulation and GI-cytoprotection, the other through actin polymerization and systemic cell migration make them uniquely interesting both individually and as a combined research subject

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used trypsin digestion to show that only a central domain of a lysine-rich histone H1 from calf thymus (residues 37120) is in a folded conformation, whereas N- and C-terminal regions (residues 136 and 121213, respectively) are very accessible in chromatin and therefore likely not in a compact, folded conformation ( Grzelczak et al

Sep 1 2022;58(5):213-230