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The Minnesota Starvation Experiment, one of the most thorough studies of calorie restriction ever conducted, found that food preoccupation, cravings, and distress around eating intensified dramatically during restriction and took months to resolve after normal eating resumed

The result was hundreds of detailed light curves, each showing the change in brightness of a very precise wavelength (color) as different sides of the object rotated into view

BNIP3, a member of the pro-apoptotic protein family, is upregulated in response to hypoxic conditions and has been implicated in the induction of autophagic cell death (93)