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IGF-1 LR3 (Insulin-like Growth Factor-1 Long R3) is a modified analogue of human IGF-1 with an extended half-life due to an arginine substitution at position 3 and a 13-amino-acid N-terminal extension that reduces binding to IGF-binding proteins

[15] Serious but infrequent events-such as angioedema, bronchospasm, hypotension, or urticaria-reflect IgE-mediated hypersensitivity and may require desensitization or substitution with hydroxocobalamin

The human tripeptide GHK: A possible treatment for improving skin health

In preclinical models, it has demonstrated pro-angiogenic, cytoprotective, and anti-inflammatory properties 1-3