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Patients often start at a low dose of Accutane during the first month of treatment to assess the patients response to the medication and any side effects experienced
For instance, ICER has introduced an equal-value life-year gained (evLYG) metric to complement QALYs for severe illnesses ( [8] ), whereas NICE has formal end-of-life modifiers
Competing interests The authors affirm that their research was conducted without any commercial or financial ties that could be perceived as potential conflicts of interest
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