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The proportion of patients who discontinued for lack of glycemic control or who were rescued for meeting prespecified glycemic criteria was 15% in the saxagliptin 2.5 mg add-on to metformin HCl group, 13% in the saxagliptin 5 mg add-on to metformin HCl group, and 27% in the placebo add-on to metformin HCl group

Glp-1 drugs assist in regulating blood sugar by increasing the secretion of insulin, reducing the speed in a patients stomach emptying

In this study, we also found both PKA inhibitors and PI3K inhibitors abrogated the anti-apoptotic effect of GLP-1 in RINm5F cells (Fig

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