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The results demonstrate that l-carnitine can be administered as a preventive intervention to reduce the reproductive damage caused by high-altitude hypobaric and hypoxic environments and improve semen quality in a rat model

The architecture of these sites creates quasi-synaptic microdomains in which local concentrations can reach 10-100 M, thereby overcoming the low affinity (roughly K d approx 20-30 M) of the mitochondrial calcium uniporter (mtCU) ( 2+ creates microdomains that facilitate the activation of mtCU ( 2+ enters the mitochondrial matrix, it acts as a critical regulator of the Krebs cycle

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Zapata-Prez, R