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These pots (30 cm 25 cm 15 cm, 0.075-m 2 surface area) were filled with 9 L of hydroponic solution containing the following macroelements and microelements: 1 mM of NH 4 NO 3 , 0.6 mM of NaH 2 PO 4 H 2 O, 0.3 mM of K 2 SO 4 , 0.2 mM of CaCl 2 , 0.4 mM of MgCl 2 6H 2 O, 45 M of Fe-EDTA, 50 M of H 3 BO 3 , 9 M of MnCl 2 4H 2 O, 0.3 M of CuSO 4 5H 2 O, 0.7 M of ZnSO 4 7H 2 O, and 0.1 M of Na 2 MoO 4 2H 2 O

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Yoon S, Seger R (2006) The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

After stopping a CYP3A4 inhibitor, as the effects of the inhibitor decline, it may result in lower codeine levels, greater norcodeine levels, and less metabolism via CYP2D6 with resultant lower morphine levels [see CLINICAL PHARMACOLOGY], resulting in decreased opioid efficacy or a withdrawal syndrome in patients who had developed physical dependence to codeine