glp 1 and alzheimer's Coveted GLP-1 Drugs Show Early Promise in Disease 🧠✨ New research is uncovering

10.1016/j.fct.2023.114090 94 WdowiakA.BakalczukS.FilipM.LaganaA

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With its localization to the SR, nNOS regulates the S-nitrosylation of the calcium release channels, the type 2 ryanodine receptors (RYR2) resulting in release of stored calcium, The localization of nNOS in the plasma membrane allows for direct S-nitrosylation of L-type Ca 2+ channels resulting in increased influx of calcium