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In a study by Locharernkul et al, some patients who developed either carbamazepine- or phenytoin-induced SJS were noted to have been exposed, and demonstrated tolerance, to other antiepileptics (phenytoin, phenobarbital, valproic acid, carbamazepine, and/or lamotrigine)
Antioxidant treatments tend to decrease the epidermal inflammation by inactivating the free radicals and stabilize the membrane and prevent new epidermal destruction.[] PEMPHIGUS VULGARIS In pemphigus vulgaris, increased production of ROS from activated neutrophils has been found to decrease the concentrations of antioxidants in plasma and RBCs, resulting in oxidative stress
Pro Tip: For best results, always apply serum on clean, dry skin and follow with cream while skin is slightly damp to lock in moisture