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When 1500 mg metformin or placebo was given with a mixed liquid meal in participants with well-controlled type 2 diabetes (mean HbA 1c 48 mmol/mol [6.5%]), the overall postprandial GLP-1 response was greater with metformin than placebo, but this increase was evident approximately 2 h after the meal [14]

If it was reconstituted in bacteriostatic water, inspect it visually any cloudiness, particulates, or discoloration means the peptide has degraded irreversibly and should be discarded

Other studies in adults with metabolic syndrome have shown that it may reduce insulin resistance and lower fasting blood glucose and HbA1c levels

Some are exaggerated