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Viral infections are sensed by innate immunity through pattern recognition receptors (PRRs), including Toll-like receptor 3 (TLR3), retinoic acid-inducible protein I and melanoma differentiation-associated gene 5

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doi:10.1038/178064a0

Services and treatment for children with cleft lip or cleft palate varies, depending on the severity of the cleft, the childs age, the childs needs and whether there are any other problems associated with the cleft