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The results demonstrated that a classic protein kinase C (cPKC) dependent phosphorylation of cytoplasmic GSTP at Ser184 occurred in macrophages in response to lipopolysaccharide (LPS) stimulation

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22 If this precedent is broadly applied, it could result in the removal of the majority of device-related patents from the Orange Book, significantly weakening the ability of innovators to delay generic entry through secondary patent litigation