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People with very fair skin often carry MC1R gene variants (like R151C or R160W) that produce a receptor less responsive to melanocortin signaling

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Cold sores are caused by herpes simplex virus type 1 (HSV-1) and reactivate due to triggers including stress, illness, and immune changes

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It would be interesting to investigate if increased -glutamylcysteine could explain the drug resistance observed in tumours associated with -glutamyltransferase overexpression 26

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