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However, increased oxidative stress (due to UA-induced ROS production from endothelial cells, vascular smooth muscle cells, macrophages and blood-born cells, like monocytes) and pro-inflammatory state induced by the presence of UA within the atherosclerotic plaques promote atherosclerotic plaque propagation and instability

coli bacteriophage T3, which reduced the levels of S-adenosylmethionine, a precursor to ACC

Epididymosomes further deliver numerous proteins to sperm, including enzymes, chaperones, and structural proteins like sperm adhesion molecule 1, which participates in zona pellucida binding, prevents premature acrosome reaction, and protects against oxidative damage ( When sperm traverse the female reproductive tract, endometrial cell-derived EVs interact with the sperm surface