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In dogs experiencing illness-related oxidative stress, antioxidant support has been discussed as one way to help manage that burden, which may show up as improved overall resilience rather than a single symptom shift (Hagen DM, 2019)

Improvement continues beyond that with sustained maintenance

Chronic obstructive pulmonary disease (COPD) Clinical correlation analysis shows that LONP1 protein expression in the airway epithelium of patients with severe COPD is markedly reduced compared with healthy individuals, and its expression level negatively correlates with the squamous metaplasia score [74]

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