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Presumably, oxidative stress is involved in the pathogenesis and complications associated with all three types of DM, and GPx1 plays a critical role in the regulation of oxidative stress [60]

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In some studies, brain atrophy and behavioral abnormalities were observed in EAAC1 KO mice at 11 months old, but not at young ages 8,9 , although such degeneration has not been universally reported 75

Regulation of rat glutathione S-transferase A5 by cancer chemopreventive agents: mechanisms of inducible resistance to aflatoxin B1