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The commentary concluded that, based on current knowledge, patients should not stop taking semaglutide on this account alone, especially given potential increases in morbidity from conditions that are well controlled by semaglutide, potential adverse effects of hyperglycemia caused by abrupt cessation of treatment, and the seemingly low absolute risk of NAION

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You can practice these lifestyle changes to reduce side effects: Keep your body well hydrated by drinking adequate water

Contrave contains naltrexone, which is used to treat alcohol and opioid addiction, because it blocks opioid receptors involved in reward and pleasure responses