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We searched PubMed, using the search terms antipsychotic-induced weight gain, metabolic syndrome, cardiometabolic, pediatric OR adolescents OR child OR children, obesity, diabetes, second generation antipsychotics, neurohormone, and neuroendocrine. Our search included articles published on PubMed through October 30th 2020

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Researchers have yet to isolate the DSIP gene or identify its receptor, leading some to question whether the peptide exists naturally or only under artificial conditions