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Conversely, Melatonin significantly reduced Iba1 expression levels, potentially through the NF-B and MAPK pathways, which have been identified as key regulators of central sensitization besides the role of pro-inflammatory cytokines, IL-1, and TNF- (Fusco et al

The oral Salmonella infection in our experiment had no or little effect on liver and ileal mucosal glutathione at 4 days post infection, indicating that the organ-specific capacity to synthesise glutathione was adequate or that infection-induced oxidative stress was absent in normally fed rats (diet adequate in antioxidants)

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